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Blood And Guts
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The Alien Blood That Keeps Humans Alive

Horseshoe crabs have bright blue blood that is used to test every vaccine on the planet.

By Smartasaurus· 1 min read Wild
The Alien Blood That Keeps Humans Alive
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Human blood is red because of iron, but horseshoe crab blood is baby blue because it is built on copper. This ancient liquid is more than just a weird color; it is one of the most valuable substances in medicine.

Instead of white blood cells, these crabs use specialized cells called amebocytes. When these cells encounter even a trace of bacteria, they instantly turn into a thick gel. This 'clot' traps the invaders before they can infect the crab.

Pharmaceutical companies harvest this blue blood to test drugs and vaccines for contamination. If you have ever had an injection, your life was likely protected by a horseshoe crab. If the medicine touches a tiny drop of the crab's blood and it clots, the batch is discarded.

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There is no synthetic replacement that works as well as this 450-million-year-old biological security system. Every year, half a million crabs are captured, bled, and then released back into the wild.

Despite their name, horseshoe crabs aren't crabs at all. They are more closely related to spiders and scorpions than they are to lobsters.

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